研究团队成员列表

张万军

发布时间: 2024-07-30 16:25:32

姓       名:

张万军

职称及职务:

副研究员,硕导

招生专业:

药物分析学

研 究 方 向:

蛋白质化学与糖蛋白质组学

联系方式:

邮  箱:zwj2004zwj@126.com

电  话:010-61777107, 13693003345

主要科研领域与方向:

从事蛋白质化学与糖蛋白质组学在癌症早期诊断及治疗中的应用研究。提出了多种基于化学标记/衍生化方法的低丰度糖蛋白富集、在线深度分离、高通量质谱鉴定等研究方法,解决了低丰度糖蛋白药物靶标、生物标志物鉴定时质谱检测灵敏度低等问题。先后主持国家重点研发计划课题、国家自然科学基金等项目,累计到位经费1000余万元。在 Molecular cell、Analytical Chemistry、Chemical Communications 等高水平杂志发表第一/通讯作者研究性论文20余篇,影响因子累计大于100,单篇最高影响因子19.7。授权国家发明专利5项。

代表性论文(*共同通讯作者,#共同第一作者)

1. Yuanyuan Li#, Chaoshuang Xia, Hongxian Zhao, Yuping Xie, Yangjun Zhang, Wanjun Zhang*, Yongliang Yu*, Jianhua Wang, Weijie Qin*, A new photolabeling probe for efficient enrichment and deep profiling of cell surface membrane proteome by mass spectrometry.Chinese Chemical Letters, 2023, 34(2):107377. (IF:8.455)

2. Yuanyuan Liu#, Qianying Yang, Zhuokun Du, Jiayu Liu, Yangjun Zhang, Wanjun Zhang*, and Weijie Qin*. ovel Two-Dimensional MoS2–Ti4+ nanomaterial for efficient enrichment of phosphopeptides and large-Scale identification of histidine phosphorylation by mass spectrometry.Analytical Chemistry,2022,94,43,14956–14964 . (IF: 8.008)

3. Wei Tan#, Pei Jiang#, Wanjun Zhang #, Zhaohua Hu, Shaofeng Lin, Lulu Chen, Yingge Li, Changmin Peng, Zhuqing Li, Aihua Sun, Yali Chen, Wenge Zhu, Yu Xue, Yi Yao, Xiangpan Li, Qibin Song, Fuchu He*, Weijie Qin*, Huadong Pei*. Molecular Cell, 2021,81(9):1890-1904. (IF: 19.32)

4. Xiaochao Xiang#, Fulin Guan, Fenglong Jiao, Hang Li, Wanjun Zhang*, Yangjun Zhang*, Weijie Qin*. A new urinary exosome enrichment method by a combination of ultrafiltration and TiO2 nanoparticles Analytical Methods, 2021,13(13):1591-1600.(IF: 3.52)

5. Wenhui Ma#, Hang Li, Yujie Wang, Qi Liu, Weijie Qin, Jiayu Liu*, Huan Cheng*, Wanjun Zhang*. Highly efficient TiO2-based one-step strategy for micro volume plasma-derived extracellular vesicles isolation and multiomics sample preparation. International Journal of Mass Spectrometry,2023,483:116971.(IF1.80)

姓       名:

张万军

职称及职务:

副研究员,硕导

招生专业:

药物分析学

研 究 方 向:

蛋白质化学与糖蛋白质组学

联系方式:

邮  箱:zwj2004zwj@126.com

电  话:010-61777107, 13693003345

主要科研领域与方向:

从事蛋白质化学与糖蛋白质组学在癌症早期诊断及治疗中的应用研究。提出了多种基于化学标记/衍生化方法的低丰度糖蛋白富集、在线深度分离、高通量质谱鉴定等研究方法,解决了低丰度糖蛋白药物靶标、生物标志物鉴定时质谱检测灵敏度低等问题。先后主持国家重点研发计划课题、国家自然科学基金等项目,累计到位经费1000余万元。在 Molecular cell、Analytical Chemistry、Chemical Communications 等高水平杂志发表第一/通讯作者研究性论文20余篇,影响因子累计大于100,单篇最高影响因子19.7。授权国家发明专利5项。

代表性论文(*共同通讯作者,#共同第一作者)

1. Yuanyuan Li#, Chaoshuang Xia, Hongxian Zhao, Yuping Xie, Yangjun Zhang, Wanjun Zhang*, Yongliang Yu*, Jianhua Wang, Weijie Qin*, A new photolabeling probe for efficient enrichment and deep profiling of cell surface membrane proteome by mass spectrometry.Chinese Chemical Letters, 2023, 34(2):107377. (IF:8.455)

2. Yuanyuan Liu#, Qianying Yang, Zhuokun Du, Jiayu Liu, Yangjun Zhang, Wanjun Zhang*, and Weijie Qin*. ovel Two-Dimensional MoS2–Ti4+ nanomaterial for efficient enrichment of phosphopeptides and large-Scale identification of histidine phosphorylation by mass spectrometry.Analytical Chemistry,2022,94,43,14956–14964 . (IF: 8.008)

3. Wei Tan#, Pei Jiang#, Wanjun Zhang #, Zhaohua Hu, Shaofeng Lin, Lulu Chen, Yingge Li, Changmin Peng, Zhuqing Li, Aihua Sun, Yali Chen, Wenge Zhu, Yu Xue, Yi Yao, Xiangpan Li, Qibin Song, Fuchu He*, Weijie Qin*, Huadong Pei*. Molecular Cell, 2021,81(9):1890-1904. (IF: 19.32)

4. Xiaochao Xiang#, Fulin Guan, Fenglong Jiao, Hang Li, Wanjun Zhang*, Yangjun Zhang*, Weijie Qin*. A new urinary exosome enrichment method by a combination of ultrafiltration and TiO2 nanoparticles Analytical Methods, 2021,13(13):1591-1600.(IF: 3.52)

5. Wenhui Ma#, Hang Li, Yujie Wang, Qi Liu, Weijie Qin, Jiayu Liu*, Huan Cheng*, Wanjun Zhang*. Highly efficient TiO2-based one-step strategy for micro volume plasma-derived extracellular vesicles isolation and multiomics sample preparation. International Journal of Mass Spectrometry,2023,483:116971.(IF1.80)